http://www.generef.com/ GeneRef - Science News, Genomics, Bioinformatics, Nanotechnology, A Global Resource en-us Thu, 29 Jul 2010 15:35:01 PDT kcowing@spaceref.com (Keith Cowing) mkboucher@spaceref.com (Marc Boucher) Copyright 2009, SpaceRef Interactive Inc. http://www.generef.com/images/generef.sm.jpg http://www.generef.com/ 100 25 GeneRef - Science News, Genomics, Bioinformatics, Nanotechnology, A Global Resource http://generef.com/newsstory.rss.html?pid=82595 http://generef.com/newsstory.rss.html?pid=82595 The Food and Drug Administration received reports of malignancies in children using tumor necrosis factor a (TNF) blockers, raising concerns of an associated risk and prompting an investigation. Researchers from the FDA set out to identify all reports of Thu, 29 Jul 2010 13:17:24 PDT http://generef.com/newsstory.rss.html?pid=82591 http://generef.com/newsstory.rss.html?pid=82591 Researchers have discovered a novel mechanism in Salmonella that affects is virulence and its susceptibility to antibiotics. The mechanism changes the bacteria's production of proteins in a previously unheard of manner. It allows Salmonella to selectivel Thu, 29 Jul 2010 13:17:23 PDT http://generef.com/newsstory.rss.html?pid=82592 http://generef.com/newsstory.rss.html?pid=82592 Some trees growing in nutrient-poor forest soil may get what they need by cultivating specific root microbes to create compounds they require. These microbes are exceptionally efficient at turning inorganic minerals into nutrients that the trees can use. Thu, 29 Jul 2010 13:17:23 PDT http://generef.com/newsstory.rss.html?pid=82583 http://generef.com/newsstory.rss.html?pid=82583 A type of prostate cell that has been largely ignored by cancer researchers can trigger malignant prostate cancer. The studies provide researchers with a new tool for exploring the genetic changes that lead to prostate cancer. The advance may help in deve Thu, 29 Jul 2010 11:17:22 PDT http://generef.com/newsstory.rss.html?pid=82582 http://generef.com/newsstory.rss.html?pid=82582 Researchers have discovered an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly used against ovarian cancer. Thu, 29 Jul 2010 11:17:21 PDT http://generef.com/newsstory.rss.html?pid=82570 http://generef.com/newsstory.rss.html?pid=82570 People with a family history of male breast cancer perceive themselves to be at higher risk of developing the disease than do patients with a family history of female breast cancer; however those with male breast cancer in their families are less likely t Thu, 29 Jul 2010 09:17:03 PDT http://generef.com/newsstory.rss.html?pid=82571 http://generef.com/newsstory.rss.html?pid=82571 The recent discovery of more than a thousand genes known as large intergenic noncoding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough is now made even more compellin Thu, 29 Jul 2010 09:17:03 PDT http://generef.com/newsstory.rss.html?pid=82565 http://generef.com/newsstory.rss.html?pid=82565 Twenty-five years after publishing the mnemonic "ABCD" to facilitate the early diagnosis of melanoma, the group who came up with that moniker says early detection remains a key factor in lowering mortality from malignant melanoma. Thu, 29 Jul 2010 07:17:20 PDT http://generef.com/newsstory.rss.html?pid=82558 http://generef.com/newsstory.rss.html?pid=82558 Public immunization efforts may be much more sensitive than previously realized to small changes in the perceived costs or risks of vaccination, scientists at Harvard University report this week. In some cases, the spread of vaccine avoidance via social n Thu, 29 Jul 2010 06:18:17 PDT http://generef.com/newsstory.rss.html?pid=82559 http://generef.com/newsstory.rss.html?pid=82559 The key to the fate of the macrophages is the balance between two kinds of eicosanoids. Eicosanoids are molecules that contribute to the control of our immune system. The genetic code of TB bacteria enables it to tip this balance in favor of necrosis, and Thu, 29 Jul 2010 06:18:17 PDT http://generef.com/newsstory.rss.html?pid=82552 http://generef.com/newsstory.rss.html?pid=82552 Scientists in Japan may have developed a way to accurately predict those patients who will resist treatment with imatinib, which is the standard of care for chronic myeloid leukemia. Wed, 28 Jul 2010 21:17:03 PDT http://generef.com/newsstory.rss.html?pid=82544 http://generef.com/newsstory.rss.html?pid=82544 Men who develop prostate cancer, especially the more aggressive and dangerous forms that spread throughout the body, tend to retain denser bones as they age than men who stay free of the disease, suggests new research from Johns Hopkins and the National I Wed, 28 Jul 2010 13:17:22 PDT http://generef.com/newsstory.rss.html?pid=82538 http://generef.com/newsstory.rss.html?pid=82538 Stronger suction is required to smoke "electronic cigarettes" than conventional brands, with possible adverse effects on human health, researchers at the University of California, Riverside report. Using a smoking machine to compare the smoking properties Wed, 28 Jul 2010 11:17:03 PDT http://generef.com/newsstory.rss.html?pid=82523 http://generef.com/newsstory.rss.html?pid=82523 Researchers have found that an enzyme in the bacteria that causes cholera uses a previously unknown mechanism in providing the bacteria with energy. Because the enzyme is not found in most other organisms, including humans, the finding offers insights int Wed, 28 Jul 2010 09:17:20 PDT http://generef.com/newsstory.rss.html?pid=82520 http://generef.com/newsstory.rss.html?pid=82520 Researchers at the University of California, San Francisco propose that treatments used on liver cancers beyond the established Milan criteria for liver transplantation may be appropriate for all patients with hepatocellular carcinoma who are listed for t Wed, 28 Jul 2010 07:17:21 PDT http://generef.com/newsstory.rss.html?pid=82503 http://generef.com/newsstory.rss.html?pid=82503 Current research suggests that taking morphine can block new blood vessel and tumor growth. The related report by Koodie et al, "Morphine suppresses tumor angiogenesis through a HIF1α/p38MAPK pathway," appears in the August 2010 issue of the American Jou Tue, 27 Jul 2010 21:17:22 PDT http://generef.com/newsstory.rss.html?pid=82492 http://generef.com/newsstory.rss.html?pid=82492 To take full advantage of recent increased financial commitments from some governments, international agencies, and philanthropies, accurate and up-to-date mapping of neglected tropical diseases (NTDs) needs to be implemented to help improve the precision Tue, 27 Jul 2010 14:19:17 PDT http://generef.com/newsstory.rss.html?pid=82487 http://generef.com/newsstory.rss.html?pid=82487 The identification of an oncogene specific to lung squamous cell carcinoma suggests that genetic activation of this oncogene could be used as an identification marker for this type of lung cancer. Tue, 27 Jul 2010 14:17:18 PDT http://generef.com/newsstory.rss.html?pid=82486 http://generef.com/newsstory.rss.html?pid=82486 In our editorial this month the PLoS Medicine editors argue that the time has come to integrate prevention and treatment of HIV into maternal and child health-care programs. Tue, 27 Jul 2010 14:17:17 PDT http://generef.com/newsstory.rss.html?pid=82469 http://generef.com/newsstory.rss.html?pid=82469 NYU Langone Medical Center has begun a clinical trial offering vascular-targeted photodynamic therapy to patients with localized prostate cancer. This novel, minimally invasive procedure uses a light-activated drug to deliver light energy waves by way of Tue, 27 Jul 2010 13:17:03 PDT